YX0798 is a selective and orally active CDK9 inhibitor (Kd: 0.28 nM). YX0798 downregulates the oncoprotein c-MYC and pro-survival protein MCL-1. YX0798 disrupts the cell cycle and results in transcriptomic reprogramming, eventually leading to cell apoptosis. YX0798 has antitumor activity[1].
Molecular Weight:
465.86
Purity:
98.90
Formula:
C21H19ClF3N5O2
Target:
Apoptosis,Bcl-2 Family,CDK,c-Myc
Application Notes:
MCE Product type: Reference compound
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