SOS1-IN-19 (Compound 10i) is a potent inhibitor of SOS1 (Son of Sevenless 1) with an IC50 value of 165.2 nM. SOS1-IN-19 blocks KRAS activation by preventing GDP/GTP exchange in KRAS signaling pathway. SOS1-IN-19 is promising for research of KRAS-driven cancers (e.g., NSCLC and colorectal cancer)[1].
Molecular Weight:
490.52
Formula:
C24H29F3N6O2
Target:
SOS1
Application Notes:
MCE Product type: Reference compound1
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