alpha-Glucosidase-IN-92 (compound 14b) is a non-competitive inhibitor targeting alpha-glucosidase (IC50=64.0 µM), with better inhibitory potency than Acarbose (HY-B0089) (IC50=750 µM). alpha-Glucosidase-IN-92 has good oral bioavailability and can cross the blood-brain barrier. alpha-Glucosidase-IN-92 can delay carbohydrate hydrolysis and reduce postprandial blood glucose. alpha-Glucosidase-IN-92 can be used in anti-glycemic research for type 2 diabetes[1].
Molecular Weight:
515.57
Formula:
C30H25N7O2
Target:
Glycosidase
Application Notes:
MCE Product type: Reference compound1
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