DNDI-6510 (Compound (S)-x38) is a non-covalent SARS-CoV-2 MPro inhibitor with a IC50 of 0.04 µM. DNDI-6510 has a potent antiviral activity across SARS-CoV-2 and its variants as well as a weak efficacy to SARS-CoV-1. DNDI-6510 significantly improves drug exposure in metabolically humanized mice model (8HUM)[1].
Molecular Weight:
474.94
Formula:
C26H23ClN4O3
Target:
Cytochrome P450,SARS-CoV,Virus Protease
Application Notes:
MCE Product type: Reference compound1
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