PI3Kalpha-IN-26 (Compound 11e) is a PI3Kalpha inhibitor with an IC50 of 75.31 nM. PI3Kalpha-IN-26 has a broad-spectrum anticancer activity, such as leukemia, colon and breast cancer, without significant cytotoxic effect on the normal Vero cells (mean IC50s of 2.74, 3.50, 3.34 and 85.29 µM, respectively)[1].
Molecular Weight:
498.02
Formula:
C24H20ClN3O3S2
Target:
CDK,PI3K
Application Notes:
MCE Product type: Reference compound1
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