CDK8-IN-19 (Compound 3d) is a CDK8 inhibitor with an IC50 of 25.08 nM. CDK8-IN-19 has a broad-spectrum anticancer activity, such as leukemia, melanoma and breast cancer, without significant cytotoxic effect on the normal Vero cells (mean IC50s of 2.87, 3.65, 3.79 and 45.48 µM, respectively)[1].
Molecular Weight:
408.32
Formula:
C17H11Cl2N3OS2
Target:
CDK,PI3K
Application Notes:
MCE Product type: Reference compound1
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