EP2 receptor antagonist-3 is a selective EP2 receptor antagonist (IC50: 8 nM in hEP2 SPA assay, 50 nM in hEP2 cAMP assay). EP2 receptor antagonist-3 increases the macrophage-mediated clearance of Amyloid-beta plaques. EP2 receptor antagonist-3 can be used for the study of alzheimers diseases[1].
Molecular Weight:
423.87
Purity:
99.08
CAS Number:
[1799626-16-6]
Formula:
C23H19ClFN3O2
Target:
Amyloid-beta,Prostaglandin Receptor
Application Notes:
MCE Product type: Reference compound
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