Cys-MC-GGFG-Dxd, CAS [[3025787-83-8]]

Product Overview

• Article Name: Cys-MC-GGFG-Dxd, CAS [[3025787-83-8]]
• Biozol Catalog Number: MCE-HY-176415
• Supplier Catalog Number: HY-176415
• Alternative Catalog Number: MCE-HY-176415-50MG,MCE-HY-176415-25MG,MCE-HY-176415-100MG,MCE-HY-176415-5MG,MCE-HY-176415-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Cys-MC-GGFG-Dxd is a cysteine-modified, cleavable ADC drug-linker conjugate. Cys-MC-GGFG-Dxd consists of a maleimidocaproyl-glycine-glycine-L-phenylalanine-glycine (MC-GGFG) linker and an Exatecan (HY-13631) derivative (DXd) (HY-13631D) payload. Cys-MC-GGFG-Dxd can be further conjugated to anti-HER2 IgG1kappa antibody for the synthesis of antibody-drug conjugates (ADC), such as the breast cancer-targeting ADC compound Fam-trastuzumab deruxtecan-nxki (Enhertu)[1].

Product Properties

• Molecular Weight: 1155.21
• Purity: 99.01
• CAS Number: [3025787-83-8]
• Formula: C55H63FN10O15S
• Target: Drug-Linker Conjugates for ADC

Application Notes

• Application Notes: MCE Product type: ADC Related