Subquinocin is a tumor suppressor CYLD inhibitor that inhibits USP family deubiquitinases (DUBs) activity of CYLD with an IC50 of 30 µM. Subquinocin enhances the activation of NF-kappaB and IFN pathways by inhibiting CYLD. Subquinocin promotes RIG-I-mediated activation of IRF3/IRF7 in the interferon pathway. Subquinocin can be used for the research of cancer and neurodegenerative diseases[1].
Molecular Weight:
405.51
Purity:
99.83
Formula:
C20H27N3O4S
Target:
Deubiquitinase,IFNAR,NF-kappaB
Application Notes:
MCE Product type: Reference compound
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