(R)-CDK2 degrader 6 is the R-enantiomer of CDK2 degrader 6 (HY-176444), a cereblon-based molecular glue degrader of CDK2 with a DC50 of 27 nM. (R)-CDK2 degrader 6 induces ubiquitination and proteasomal degradation of CDK2 by bridging cereblon and CDK2. (R)-CDK2 degrader 6 is applicable for cancer research[1].
Molecular Weight:
511.44
Purity:
99.55
CAS Number:
[3083777-50-5]
Formula:
C23H22F5N5O3
Target:
CDK,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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