KDX1381 is a bivalent CK2alpha inhibitor (IC50: 17 nM, KD: 54 nM). KDX1381 has antitumor activity in mouse 786-O and A375 tumor xenograft models. KDX1381 combined with VEGFR inhibitors or DNA damaging agents enhances antitumor efficacy in mouse hepatocellular carcinoma and glioma models[1].
Molecular Weight:
634.70
CAS Number:
[2757728-47-3]
Formula:
C32H32F2N6O4S
Target:
Casein Kinase
Application Notes:
MCE Product type: Reference compound
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