ANT2681 is a potent NDM inhibitor with a Ki value of 0.04 µM against NDM-1. ANT2681 also inhibits other MBLs, such as VIM-1 and IMP-1 with Ki values of 0.63 µM and 3.81 µM, respectively. ANT2681 can be used in combination with Meropenem (HY-13678) to inhibit infections caused by NDM-producing Enterobacteriaceae[1].
Molecular Weight:
435.39
CAS Number:
[2270184-16-0]
Formula:
C12H11F2N7O5S2
Target:
Bacterial,Beta-lactamase
Application Notes:
MCE Product type: Reference compound
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