PY-PAP is a photoactivatable affinity probe and a derivative of PY-60 (HY-141644). PY-PAP retains the cellular function of activating YAP transcriptional activity. In 293A cells, PY-PAP can label cathepsin D (CTSD) and annexin A2 (ANXA2) through ultraviolet crosslinking and click reactions. PY-PAP plays a key role in identifying ANXA2 as the specific target of PY-60[1].
Molecular Weight:
462.54
CAS Number:
[2765218-57-1]
Formula:
C25H30N6O3
Target:
Annexin A,YAP
Application Notes:
MCE Product type: Reference compound
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