KMR-206 is a potent selective PARP7 inhibitor, with an IC50 of 13.7 nM. KMR-206 increases STAT1 and phospho-Tyr701-STAT1 (pSTAT1). KMR-206 induces STING degradation, increases type I IFN reporter. KMR-206 exhibits anticancer activity against lung adenocarcinoma. KMR-206 can be used in the research of colon cancer[1].
Molecular Weight:
506.53
CAS Number:
[2992741-10-1]
Formula:
C29H23FN6O2
Target:
IFNAR,PARP,STAT,STING
Application Notes:
MCE Product type: Reference compound
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