MF-DH-300 is a 15-PGDH inhibitor with an IC50 of 1.6 nM. MF-DH-300 blocks binding of 15-PGDH to PGE2 and increases stem cell proliferation and muscle force, as well as improves mitochondrial function. MF-DH-300 increases survival motor neuron (SMN) protein expression. MF-DH-300 can be used for muscle disorders like spinal muscular atrophy (SMA) research[1].
Molecular Weight:
330.38
Purity:
99.53
CAS Number:
[2673403-86-4]
Formula:
C20H18N4O
Target:
15-PGDH
Application Notes:
MCE Product type: Reference compound
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