VVD-849 is a RAS ligand. VVD-849 binds covalently to cysteine 242 in the RAS binding domain of PI3K p110alpha and promotes RAS/PI3K interaction. VVD-849 partially inhibits pAKT(S473) in HER2 over-expressing tumors. VVD-849 can be used cancers like breast cancer research[1].
Molecular Weight:
636.15
Purity:
99.76
CAS Number:
[3055321-14-4]
Formula:
C29H31ClFN3O6S2
Target:
PI3K,Ras
Application Notes:
MCE Product type: Reference compound
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