PNR-3-80, CAS [[1424353-63-8]]

Catalog Number: MCE-HY-176835
Article Name: PNR-3-80, CAS [[1424353-63-8]]
Biozol Catalog Number: MCE-HY-176835
Supplier Catalog Number: HY-176835
Alternative Catalog Number: MCE-HY-176835-10MG,MCE-HY-176835-25MG,MCE-HY-176835-50MG,MCE-HY-176835-100MG,MCE-HY-176835-5MG
Manufacturer: MedchemExpress
Category: Biochemikalien
PNR-3-80 is an endonuclease G (ENDOG) inhibitor with an IC50 of 0.67 µM. As a non-competitive binder to the ENDOG-substrate complex, PNR-3-80 specifically inhibits the endonuclease activity of ENDOG. PNR-3-80 reduces cell death induced by Cisplatin (HY-17394) and Docetaxel (HY-B0011), and inhibits DNA damage and autophagy (autophagy) induced by Etoposide (HY-13629). PNR-3-80 can be used in studies related to cell injury[1][2].
Molecular Weight: 459.90
CAS Number: [1424353-63-8]
Formula: C24H14ClN3O3S
Target: Autophagy,Endonuclease
Application Notes: MCE Product type: Reference compound