PI3K/mTOR-IN-18, CAS [[1220699-39-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-176854
Supplier Catalog Number:
HY-176854
Alternative Catalog Number:
MCE-HY-176854-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PI3K/mTOR-IN-18 (Compound 12) is a highly selective dual PI3K/mTOR inhibitor. PI3K/mTOR-IN-18 shows antitumor effects via competitive binding to PI3Kalpha (Ki=0.130 nM) and mTOR (Ki=0.111 nM). PI3K/mTOR-IN-18 blocks the PI3K/AKT/mTOR pathway and inhibits tumor cell proliferation (IC50=144 nM). PI3K/mTOR-IN-18 is promising for research of solid tumors (e.g., breast, NSCLC)[1].
Molecular Weight:
405.45
CAS Number:
[1220699-39-7]
Formula:
C22H23N5O3
Target:
mTOR,PI3K
Application Notes:
MCE Product type: Reference compound
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