Hakin-1 is a E3 Ubiquitin-Ligase Hakai inhibitor. Hakin-1 blocks Hakai-mediated global ubiquitination and specific ubiquitination of E-cadherin and inhibits epithelial-mesenchymal transition (EMT) progression. Hakan-1 inhibits tumor progression and cancer metastasis. Hakin-1 can be used for the study of carcinoma such as colorectal cancer[1].
Molecular Weight:
385.35
CAS Number:
[346660-34-2]
Formula:
C16H11N5O5S
Target:
Cadherin,E1/E2/E3 Enzyme
Application Notes:
MCE Product type: Reference compound
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