TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC50 of 0.88 µM. TCB-32 hydrochloride significantly increases cell proliferation through activating FGFR1 signaling pathway as bFGF and its downstream ERK 1/2 with excellent thermal stability. TCB-32 hydrochloride can replace bFGF in serum-free cell culture media. TCB-32 hydrochloride can be used for tissue repair and wound healing related diseases like psoriasis and eczema research[1][2].
Molecular Weight:
854.62
Purity:
95.53
CAS Number:
[169764-95-8]
Formula:
C32H44Cl4N18O2
Target:
ERK,FGFR
Application Notes:
MCE Product type: Reference compound1
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