Glucocorticoid receptor/IL-6-IN-1, CAS [[1198784-71-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-176876
Supplier Catalog Number:
HY-176876
Alternative Catalog Number:
MCE-HY-176876-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Glucocorticoid receptor/IL-6-IN-1 (Compound 35) is a selective dual inhibitor targeting the glucocorticoid receptor (GR) and IL-6 signaling pathway (IC50 values of 120 nM and 59 nM, respectively). Glucocorticoid receptor/IL-6-IN-1 inhibits IL-6-induced JAK/STAT3 phosphorylation, blocking inflammatory cytokine transcription. Glucocorticoid receptor/IL-6-IN-1 is promising for research of inflammatory diseases like rheumatoid arthritis and asthma[1].
