BRI-12349 (Compound 50) is a dual antagonist of CysLT1R/CysLT2R with Ki values of 1.03 and 6.46 µM. BRI-12349 can inhibit the generation of IP1 induced by LTD4 (the main ligand of CysLTs). BRI-12349 can be used for the research of immunology and inflammation, such as asthma[1].
Molecular Weight:
399.45
CAS Number:
[920707-33-1]
Formula:
C17H13N5O3S2
Target:
Leukotriene Receptor
Application Notes:
MCE Product type: Reference compound
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