AfaPhos1 is a new, Afatinib (HY-10261)-based EGFR PhosTAC. AfaPhos1 induces EGFR dephosphorylation at both pY1068 and pY845. AfaPhos1 induces Apoptosis. AfaPhos1 has anticancer activity against non-small cell lung cancer[1].
Molecular Weight:
1222.79
Formula:
C64H77ClFN7O14
Target:
Apoptosis,Drug Derivative,EGFR
Application Notes:
MCE Product type: Reference compound
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