Tubulin-IN-51, CAS [[849550-36-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-177021
Supplier Catalog Number:
HY-177021
Alternative Catalog Number:
MCE-HY-177021-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Tubulin-IN-51 is an orally available, potent tubulin inhibitor (IC50 = 31 nM). Tubulin-IN-51 promotes tubulin polymerization in vitro and does not compete with Paclitaxel (HY-B0015) for binding. Tubulin-IN-51 inhibits the binding of Vinblastine (HY-13780) to tubulin. Tubulin-IN-51 downregulates the proportion of cells in the G1 phase and induces apoptosis. Tubulin-IN-51 inhibits tumor growth in multiple nude mouse xenograft models[1].
Molecular Weight:
464.82
CAS Number:
[849550-36-3]
Formula:
C18H18ClF5N6O
Target:
Apoptosis,Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound
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