AS2795440 is a PIKfyve inhibitor. AS2795440 selectively inhibits proinflammatory cytokine such as IL-12p40 and IL-6 production and B cell activation without affecting Ca2+ signaling. AS2795440 significantly reduces joint inflammation and bone loss in adjuvant-induced arthritis (AIA) mice model. AS2795440 can be used for inflammatory and autoimmune diseases like rheumatoid arthritis, psoriasis and inflammatory bowel disease research[1].
Molecular Weight:
480.60
CAS Number:
[2171506-45-7]
Formula:
C29H32N6O
Target:
Interleukin Related,MHC,PIKfyve
Application Notes:
MCE Product type: Reference compound
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