ADT-1004 is an orally active prodrug of ADT-007 (HY-157887). ADT-007 is a reversible, highly potent and selective pan-RAS inhibitor that binds to the nucleotide-free conformation of RAS proteins and blocks their GTP activation, thereby inhibiting the downstream MAPK and AKT signaling pathways. ADT-1004 can be used for the research of pancreatic ductal adenocarcinoma[1].
Molecular Weight:
589.65
Purity:
98.16
CAS Number:
[1945941-72-9]
Formula:
C33H36FN3O6
Target:
Drug Intermediate,Ras
Application Notes:
MCE Product type: Reference compound
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