CHNQD-01281, CAS [[2762488-97-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-177270
Supplier Catalog Number:
HY-177270
Alternative Catalog Number:
MCE-HY-177270-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
CHNQD-01281, a derivative of Brefeldin A (HY-16592), is a EGFR modulator. CHNQD-01281 has strong antiproliferative activities against cancer cells (IC50: 0.079 and 0.081 µM for T24 and J82 cells, respectively). CHNQD-01281 regulates both EGFR/PI3K/AKT and EGFR/ERK pathways and mediates the chemotactic effect of chemokines on immune effector cells. CHNQD-01281 remarkably inhibits tumor growth in T24 xenograft mice model and prolongs the survival time in MB49 allogeneic mice model via inducing infiltration of cytotoxic T cells[1].
Molecular Weight:
411.49
CAS Number:
[2762488-97-9]
Formula:
C24H29NO5
Target:
Drug Derivative,EGFR
Application Notes:
MCE Product type: Natural Products
* VAT and and shipping costs not included. Errors and price changes excepted
