BTT-3034, a sulfonamide derivative, is an alpha2beta1 integrin inhibitor. BTT-3034 inhibits cell adhesion to rat tail collagen I with an EC50 of 160 nM and a corresponding Emaxof 86%. BTT-3034 inhibits collagen binding by an alpha2 variant carrying the conformationally activating E318W mutation[1].
Molecular Weight:
467.56
CAS Number:
[1259029-47-4]
Formula:
C22H21N5O3S2
Target:
Integrin
Application Notes:
MCE Product type: Reference compound
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