STING agonist-45, CAS [[2361424-97-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-177338
Supplier Catalog Number:
HY-177338
Alternative Catalog Number:
MCE-HY-177338-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
STING agonist-45 is a selective STING agonist (EC50 = 0.28 µM). STING agonist-45 activates the innate immune response through the cGAS-STING pathway, upregulating key markers such as p-TBK1 and IRF3. STING agonist-45 exhibits robust STING activation in human peripheral blood mononuclear cells (PBMCs), inducing the production of type I interferons (such as IFN-beta) and downstream cytokines (such as TNF-alpha and IL-6). STING agonist-45 enhances anti-tumor immunity, inhibits tumor growth, and increases CD8+ T cell infiltration in mouse models. STING agonist-45 is promising for the study of STING-related diseases[1][2].
