Rostudirsen, CAS [[3028750-59-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-177484
Supplier Catalog Number:
HY-177484
Alternative Catalog Number:
MCE-HY-177484-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
DYNE-251 Oligomer
Rostudirsen, one of the components of Zeleciment rostudirsen (HY-177485), is a phosphorodiamidate morpholino oligomer. Zeleciment rostudirsen consists of Rostudirsen (HY-177484) conjugated to a fragment antibody (Fab), Zeleciment (HY-P990780), which binds to the transferrin receptor 1 (TfR1) that is highly expressed in muscle. It is designed to enable targeted muscle tissue delivery and promote exon skipping in the nucleus, allowing muscle cells to create internally shortened, near full-length dystrophin protein.