SKLB-03220, CAS [[2852050-29-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-177497
Supplier Catalog Number:
HY-177497
Alternative Catalog Number:
MCE-HY-177497-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SKLB-03220 is a selective and orally active EZH2 covalent inhibitor with an IC50 of 1.72 nM for EZH2MUT. SKLB-03220 exhibits weak activities against other tested histone methyltransferases (HMTs) and kinases. SKLB-03220 displays noteworthy potency against ovarian cancer cell lines and induces cell apoptosis. SKLB-03220 significantly inhibits tumor growth in PA-1 xenograft model. SKLB-03220 can be used for the study of ovarian cancer[1].
Molecular Weight:
556.70
CAS Number:
[2852050-29-2]
Formula:
C33H40N4O4
Target:
Apoptosis,Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted