Delpacibart braxlosiran, CAS [[2929261-85-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-177566
Supplier Catalog Number:
HY-177566
Alternative Catalog Number:
MCE-HY-177566-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Del-brax, AOC 1020
Delpacibart braxlosiran (Del-brax), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) (HY-P990051) that binds to the transferrin receptor 1 (TfR1) conjugated with a siRNA targeting DUX4 (Double homeobox protein) mRNA. It is used for the study of Facioscapulohumeral Muscular Dystrophy (FSHD). The abnormal expression of DUX4 protein leads to changes in gene expression in muscle cells that are associated with the life-long, progressive loss of muscle function in patients with FSHD[1].
