Bazlitoran (IMO-8400) is an oligonucleotide-based TLR7/8/9 antagonist. Bazlitoran blocks the activation of Toll-like receptors 7, 8, and 9. Bazlitoran inhibits cytokine responses mediated by Toll-like receptors 7, 8, and 9. Bazlitoran is associated with injection site reactions. Bazlitoran improves moderate-to-severe plaque psoriasis[1][2].
Molecular Weight:
5800.70
CAS Number:
[1378549-07-5]
Formula:
C179H233N52O101P17S17
Target:
Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Oligonucleotides
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