GSPT1 degrader-11 is a CRBN-dependent G1 to S phase transition 1 (GSPT1) molecular glue degrader (DC50 = 67.7 nM, Dmax = 97%). GSPT1 degrader-11 can inhibit MDA-MB-231 CRBN-WT cells proliferation (IC50 = 2.07 µM). GSPT1 degrader-11 can be used for the research of cancer[1].
Molecular Weight:
771.87
Formula:
C41H45N11O5
Target:
Molecular Glues
Application Notes:
MCE Product type: Reference compound
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