TR-213 is a potent molecular glue degrader that targets Cyclin K (CDK). TR-213 induces 91% and 56% decrease in CDK12 and Cyclin at 1 µM. TR-213 can inhibit RNA polymerase II activity and regulates alternative polyadenylation (APA) activity. TR-213 can be used for the research of cancer[1].
Molecular Weight:
388.42
CAS Number:
[2980502-40-5]
Formula:
C22H20N4O3
Target:
CDK,DNA/RNA Synthesis,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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