MEK-IN-7 (compound WX086) is potent, orally active and selective MEK inhibitor (MEK1 IC50 = 29.62 nM). MEK-IN-7 inhibits HT29 and A375 cell proliferation with IC50s of 0.62 and 0.40 nM. MEK-IN-7 inhibits tumor growth in a HL-29 xenograft mouse model. MEK-IN-7 can be used for melanoma and colon cancer research[1].
Molecular Weight:
649.47
CAS Number:
[2256822-22-5]
Formula:
C27H25FIN3O5S
Target:
MEK
Application Notes:
MCE Product type: Reference compound
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