EGFR-IN-174 is a potent EGFR inhibitor (IC50 = 0.17 µM) and also displays VEGFR-2 inhibition (IC50 = 0.2007 µM). EGFR-IN-174 exhibits potent anticancer effects with low cytotoxicity to normal cells. EGFR-IN-174 induces G2/M and Pre-G1 phase arrest and significantly triggers apoptosis. EGFR-IN-174 can be used in cancer research, such as colorectal carcinoma, hepatocellular carcinoma, and breast cancer[1].
Molecular Weight:
385.57
Formula:
C16H23N3O2S3
Target:
Apoptosis,EGFR,VEGFR
Application Notes:
MCE Product type: Reference compound
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