FLT3-IN-34, CAS [[3020729-11-4]] Preis auf Anfrage

Product Overview

• Article Name: FLT3-IN-34, CAS [[3020729-11-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-178020
• Supplier Catalog Number: HY-178020
• Alternative Catalog Number: MCE-HY-178020-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

FLT3-IN-34 is a FLT3 inhibitor, with an IC50 value of 1.4 nM. FLT3-IN-34 blocks the phosphorylation of FLT3 and its downstream signaling molecules AKT and ERK1/2. FLT3-IN-34 induces concentration-dependent G0/G1 phase arrest and mild apoptosis in FLT3-ITD-positive MV4-11 cells. FLT3-IN-34 shows potent anti-proliferative activity against FLT3-ITD-positive MV4-11 cells (IC50 = 14.95 nM) and MOLM-13 (IC50 = 18.5 nM). FLT3-IN-34 can be used for the study of FLT3-positive acute myeloid leukemia (AML)[1].

Product Properties

• Molecular Weight: 417.46
• CAS Number: [3020729-11-4]
• Formula: C23H23N5O3
• Target: Akt,Apoptosis,ERK,FLT3

Application Notes

• Application Notes: Reference compound