CDK2-IN-47 is a potent CDK2 inhibitor with an IC50 of 0.21 µM. CDK2-IN-47 exhibits outstanding anticancer activity against MCF-7, HCT-116, and MGC-803 cell lines. CDK2-IN-47 effectively induces G1 cell cycle arrest, retinoblastoma protein (Rb) dephosphorylation, and significant apoptosis. CDK2-IN-47 can be used for the studies of breast cancer, colorectal cancer and gastric cancer[1].
Molecular Weight:
381.45
Formula:
C16H23N5O4S
Target:
Apoptosis,CDK
Application Notes:
MCE Product type: Reference compound
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