MAO-A/B-IN-5 is an orally active MAO-A (IC50 = 73.88 µM) and MAO-B (IC50 = 91.08 µM) inhibitor. MAO-A/B-IN-5 reverses Sodium nitroprusside (SNP) (HY-B0564)-induced cerebral lipid peroxidation (IC50 = 130.2 µM) and protein carbonylation (IC50 = 229.8 µM). MAO-A/B-IN-5 shows dose-dependent and time-dependent antidepressant-like efficacy in mice. MAO-A/B-IN-5 can be used for the study of depressive disorder[1].
Molecular Weight:
461.25
Formula:
C21H20BrNOSe
Target:
Monoamine Oxidase
Application Notes:
MCE Product type: Reference compound
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