FB231 is a Parkin activator. FB231 can induce mild mitochondrial stress, resulting in impaired mitochondrial function and activation of the integrated stress response. FB231 can lower the threshold for mitochondrial toxins to induce PINK1/Parkin-mediated mitophagy. FB231 can cause activation of the integrated stress response (ISR) and perturbation to iron-dependent pathways. FB231 can be used for the research of neurological disease, such as Parkinsons disease[1].
Molecular Weight:
411.46
CAS Number:
[2166045-37-8]
Formula:
C24H21N5O2
Target:
Mitochondrial Metabolism,PINK1/Parkin
Application Notes:
MCE Product type: Reference compound1
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