ARUK2010489 (Compound 23) is a potent, selective and brain-penetrant NUAK1 inhibitor with a pIC50 of 8.7. ARUK2010489 also inhibits CDK2, CDK4 and CDK6 activity, with inhibitory rate of 7%, 39% and 26% at 1 µM. ARUK2010489 can be used for the research of neurological disease, such as Alzheimers disease (AD)[1].
Molecular Weight:
406.52
Formula:
C23H30N6O
Target:
AMPK,CDK
Application Notes:
MCE Product type: Reference compound1
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