MGB4 is a DNA minor groove binder. MGB4 binds to ARE-containing DNA and inhibition of topoisomerase I activity. MGB4 can impacts key cellular pathways, including inhibition oftranslation and alterations in sphingolipid and amino acid metabolism. MGB4 also reduces spermine and spermidine metabolism companied with Doxorubicin (HY-15142A). MGB4 can be used for the research of cancer, such as Prostate cancer[1].
Molecular Weight:
739.79
Formula:
C30H36F3N9O6S2
Target:
DNA/RNA Synthesis,Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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