MDOLL-0286 is a selective Poly(ADP-ribose) Glycohydrolase (PARG) (ARH3) inhibitor with an IC50 of 2.3µM. MDOLL-0286 can inhibit ARH3s poly-ADP-ribose hydrolytic activity on cellular substrates. MDOLL-0286 can inhibit DNA damage response. MDOLL-0286 can be used for the research of cancer [1].
Molecular Weight:
299.37
Purity:
99.66
Formula:
C16H21N5O
Target:
Poly(ADP-ribose) Glycohydrolase (PARG)
Application Notes:
MCE Product type: Reference compound
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