VHR-IN-5 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC50 of 78 nM. VHR-IN-5 shows very weaker inhibitory activity against MKP-1 (IC50 = 0.78 µM), CD45 (IC50 = 0.61 µM), Cdc25A (IC50 = 3.4 µM), PTP1B (IC50 = 1.8 µM), and HePTP (IC50 = 1.5 µM). VHR-IN-5 inhibits the proliferation of HeLa cells. VHR-IN-5 can be used for the research of cervical cancer[1].
Molecular Weight:
577.69
CAS Number:
[956442-05-0]
Formula:
C28H23N3O5S3
Target:
Phosphatase
Application Notes:
MCE Product type: Reference compound
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