VHR-IN-6 is a selective vaccinia H1-related (VHR) phosphatase inhibitor with an IC50 of 74 nM. VHR-IN-6 shows very weaker inhibitory activity against MKP-1 (IC50 = 0.52 µM), CD45 (IC50 = 0.50 µM), Cdc25A (IC50 = 2.8 µM), PTP1B (IC50 = 0.42 µM), and HePTP (IC50 = 0.87 µM). VHR-IN-6 inhibits the proliferation of HeLa cells. VHR-IN-6 can be used for the research of cervical cancer[1].
Molecular Weight:
595.68
CAS Number:
[1146616-16-1]
Formula:
C28H22FN3O5S3
Target:
Phosphatase
Application Notes:
MCE Product type: Reference compound1
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