MW073 is a highly selective and orally active 5-HT2BR antagonist (IC50 =70 nM). MW073 exerts its effects by concentration-dependently inhibiting receptor activity and beta-arrestin-1 recruitment. MW073 ameliorates synaptic plasticity and behavioral deficits, including aggression, in Alzheimers disease (AD) mouse models. MW073 can be used for Alzheimers disease (AD) research[1][2].
Molecular Weight:
361.48
CAS Number:
[3048608-87-0]
Formula:
C22H27N5
Target:
5-HT Receptor,Arrestin
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
