MT-44 is a highly selective and potent mTOR inhibitor with an IC50 of 49.4 nM. MT-44 can inhibit cancer cells proliferation, migration and invasion. MT-44 can induce cells apoptosis and ROS production and cause G2/M phase arrest. MT-44 can activate the cGAS/STING pathway. MT-44 can be used for the research of cancer, such as triple-negative breast cancer[1].
Molecular Weight:
469.49
CAS Number:
[2966790-70-3]
Formula:
C26H23N5O4
Target:
Apoptosis,mTOR,Reactive Oxygen Species (ROS),STING
Application Notes:
MCE Product type: Reference compound
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