HW091077 is a highly selective P2X3 receptor antagonist with an IC50 of 17 nM. HW091077 blocks ATP-induced calcium influx and cell depolarization to inhibit cough reflex pathways. HW091077 is promising for research of chronic cough[1].
Molecular Weight:
498.49
CAS Number:
[2766757-56-4]
Formula:
C22H22F4N4O3S
Target:
P2X Receptor
Application Notes:
MCE Product type: Reference compound
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