PROTAC FAK degrader 4 (Compound 9C) is an efficient and selective FAK PROTAC degrader. PROTAC FAK degrader 4 has a DC50 of 3.6 nM in MDA-MB-231 cells. PROTAC FAK degrader 4 significantly inhibits tumor cell proliferation, migration, and invasion, and enhances chemotherapy sensitivity to cisplatin (HY-17394). PROTAC FAK degrader 4 can be used for research on cancer. (Pink: FAK Ligand (HY-43760), Blue: VHL Ligand (HY-125845), Black: Linker (HY-W208616))[1]
Molecular Weight:
1011.12
Formula:
C52H57F3N8O8S
Target:
FAK,PROTACs
Application Notes:
MCE Product type: Reference compound
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